Moreover, our results indicated that other genes associated with the cell cycle (CDK1, PRC1, ASF1B, CDKN3, DLGAP5, FOXM1, KIAA0101, CDCA3, KIF20A, NUSAP1, CENPM, PLK1, CDCA8, DTL, and CENPF) were overexpressed (FC ≥ 4) in lung cancer stem cells compared to in cancer cells. The gene discussed is PLK1; the disease is lung cancer.