Levels of circRNA TTBK2 and integrin subunit β 8 (ITGB8) are upregulated in glioma tissues and cells with downregulated miRNA-761 levels, and circRNA TTBK2 regulates cell proliferation, invasion, and ferroptosis via the miRNA-761/ITGB8 axis (180). The gene discussed is ITGB8; the disease is glioma.