The effects of other proteins, including AFF3, CPEB1, DZIP1, ENOX1, LUZP4, RAVER2, RBFOX3, RBM20, RBPMS2, SAMD4A and ZCCHC24, in the development of CRC is poorly understood and should be investigated further. The gene discussed is RBPMS2; the disease is colorectal carcinoma.