The effects of other proteins, including AFF3, CPEB1, DZIP1, ENOX1, LUZP4, RAVER2, RBFOX3, RBM20, RBPMS2, SAMD4A and ZCCHC24, in the development of CRC is poorly understood and should be investigated further. Here, SAMD4A is linked to colorectal carcinoma.