FER1L4 and liver cancer: Moreover, the expression of FER1L4 in liver cancer cell lines SK-HEP-1, Hep3B, and HUH-7 and HUH-7/DDP-resistant cell line was significantly increased compared with that of the normal liver cell line THLE-3, and among them, HUH-7/DDP-resistant strains had the highest expression of FER1L4 (Figure 1D).