TNF and inflammatory bowel disease: Yanhusuo extracts also contain berberine, which not only inhibits the proliferation of cancer cells [84] but also can be used in the treatment of inflammatory bowel disease by protecting the intestinal epithelial barrier, regulating the transcription of intestinal inflammatory cytokines, and reducing proinflammatory cytokines such as TNF-α, IL-13, IL-6, IL-8, and IFN-γ [85].