In Figures 5D, I, CLP-induced septic mice exhibited an augmented positive signals indicative of CD11b expression (versus sham group), while miR-let-7b agomir treatment reduced this effect in both the liver and lungs (p=0.01 and p=0.04, respectively), further supporting the pivotal role of miR-let-7b during sepsis. Here, ITGAM is linked to Sepsis.