The potent anti-tumor effect was observed in mice treated with CTLA4-T cells, whereas GFP-T cells did not suppress tumor growth, at the end of the experiment, all mice treated with CTLA4-T cells had significantly decreased tumor volume and tumor weight (Figures 2A–C), whereas mice in GFP-T cells treated or the control groups developed large tumors. Here, CTLA4 is linked to neoplasm.