In the multivariable analysis increased expression of MCP-3 [adjusted hazards ratio (aHR) 1.723, 95% CI 1.040 – 2.855, p=0.035] and of IL-6 (aHR 1.409, 95% CI 1.045 – 1.899, p=0.024) during active TB were significantly associated with shorter time to culture conversion (Figure 2B, Supplementary Figure 1 and Supplementary Table 3). This evidence concerns the gene IL6 and tuberculosis.