CD4 and neoplasm: We found that ATP1B3 was correlated with tumor purity (r = -0.353, p = 1.33E-11) and the B cells infiltration (r =0.266, p = 5.52E-7), CD8+ T infiltration (r = 0.249, p = 3.25E-6), CD4+ T infiltration (r = 0.169, p = 1.65E-3), Macrophage infiltration (r = 0.356, p = 1.25E-11), Neutrophil infiltration(r = 0.301, p = 1.21E-8) and Dendritic cell infiltration (r = 0.328, p = 5.46E-10) (Figure 5).