Although ATP1A2, ATP1A4, and ATP1B2 were differently expressed between HCC tissue and normal tissue, ATP1A2, ATP1B2 and ATP1A4 mRNA levels were very much low in both HCC and normal tissue, and ATP1B2 expression was slightly reduced in HCC compared to liver tissue with |log2FC|<0.5. The gene discussed is ATP1B2; the disease is hepatocellular carcinoma.