Isocitrate dehydrogenase 1 wildtype (IDH-1 wt) was observed in 68 patients (94%) with a high edema to tumor ratio and in 57 patients (79%) with a low edema to tumor ratio (p=0.01; 95%CI: 0.07-0.71, OR: 0.2 in univariate and p=0.03; 95%CI: 0.13-0.90, OR: 4.6 in multivariate analysis. Here, IDH1 is linked to neoplasm.