ERBB2 and glioblastoma: The assessment of immune infiltration is of paramount importance since the introduction of T cells with the expression of chimeric antigen receptors (CARs) directed against specific antigens (EGFRvIII-, HER2- and IL-13 Rα2 CAR T-cells) have initiated the era of personalized immunotherapy in GBM; and the results of several ongoing studies are eagerly anticipated (10, 28, 29).