CXCR3 and geroderma osteodysplastica: Increased CXCR3+ IFN-γ–producing Th17.1 cells were positively correlated with GO activity and associated with the development of very severe GO; In GC-resistant, very severe GO patients, CXCR3+ IFN-γ–producing Th17.1 cells remained at high levels in blood and orbital connective tissues, which were positively correlated with elevated triglycerides.