After adjusting for age, years since menopause, LH, E2, BMI, dyslipidaemia, diabetes, hypertension, smoking, and drinking, the ORs of declined eGFR increased across FSH quartiles in both age groups; moreover, they were higher for each FSH quartile in the older group (OR=1.461 for quartile 2, OR=2.486 for quartile 3, and OR=2.530 for quartile 4 vs quartile 1) than for the corresponding quartile in the younger group (OR=0.925 for quartile 2, OR=1.498 for quartile 3, and OR=1.755 for quartile 4 vs quartile 1) (Figure 3 and Table 5). The gene discussed is PLOD1; the disease is inherited lipid metabolism disorder.