A total of 200 genes with an evidence score >4 were included as prioritized genes, and the top 10 prioritized genes are as follows: SOD1, FUS, TARDBP, TBK1, OPTN, VCP, SETX, FIG4, SQSTM1, and VAPB. Considering that nucleotide repeat expansions in the C9orf72 and ATXN2 genes are commonly considered genetic causes of MND, the C9orf72 and ATXN2 genes were also included in the functional analysis. The gene discussed is TARDBP; the disease is mild neurocognitive disorder.