Recent findings have revealed that CXCR4 is associated with angiogenesis, inflammatory cell migration, and proliferation in IA walls (Hoh et al., 2014) and that it may play an important role in inflammatory activity in the abdominal aortic aneurysm (AAA) wall (Tanios et al., 2015). This evidence concerns the gene CXCR4 and triple-A syndrome.