Similarly, natriuretic peptide (NP) including brain natriuretic peptide (BNP), atrial natriuretic peptide (ANP), and their N-terminal counterparts (NT-pro BNP and NT-pro ANP), used to be considered as biomarkers for heart failure, have been explored as predictors of anticancer drug-induced cardiotoxicity 60-62. Here, NPPA is linked to heart failure.