FGL2 and infection: Fgl2 +/+ mice and FGL2-/- mice in intravenous infection of lymphocytic chori-omeningitis virus clone-13 (LCMV), Luft and his colleagues suggested the total number of macrophages and DC expressing CD80, CD86, MHCII and virus-specific CD8+ T cells were significantly enhanced in fgl2-/- mice in contrast to fgl2+/+ mice.