For example, CNV-Amp of genes such as FGF4, FGF19, ETV1, PMS2, RPTOR, CARD11, ERCC5 and RAC1 appeared only in the WCH-HBV-HCC group, and CNV-Amp of genes such as MET, MYC, AKT3, AGO2, BRD4 and IKBKE appeared only in the TCGA-HBV-HCC group. The gene discussed is ERCC5; the disease is hepatocellular carcinoma.