HMGB1 and neoplasm: Chemotherapy-induced ICD of tumors and the immunogenic dead tumor cells can release tumor-associated antigens (TAA) and damage-associated molecular patterns (DAMPs), including calreticulin (CRT) and high mobility group box 1 (HMGB1) (Kepp et al., 2011; Galluzzi et al., 2017; Feng et al., 2018; Wang Q et al., 2018).