On the one hand, hypoxia-inducible factor 1a (HIF-1a) has been shown to be co-expressed with VEGF in human temporal cortex and hippocampal tissue,38,39 as well as in the coriaria lactone rat model,39 and in the lithium-pilocarpine-induced status epilepticus rat model.40 Here, VEGFA is linked to status epilepticus.