Among the dysregulated genes, SCLC pathway was the topmost dysregulated pathway along with upregulation of p53, Itgb1, Cdk6, NF-κB1 and downregulation of Apaf1 following exposure to the high or the low dose of 2,4-D without LPS or in combination with LPS. Here, APAF1 is linked to small cell lung carcinoma.