FGF1 and nonpapillary renal cell carcinoma: Further, to explore the potential biological function of FGF1 in ccRCC development, we computed the basic physicochemical parameters of the protein, which result revealed that FGF1 is a hydrophilic protein weighting 17.5KD, and the protein mainly locates in the nucleoplasm or to be secreted out of cells, the estimated half-time is 30 h and tend to be unstable.