The high prevalence of this comorbidity in IPF patients is partially explained by a shared genetic predisposition to the development of both IPF and CAD by detection of specific interleukin (IL)-17 immune responses to the alpha 1 chain of collagen type V and by their correlation with human leukocyte antigen (HLA)-D15 alleles [53]. The gene discussed is IL17A; the disease is idiopathic interstitial pneumonia.