NOD2 and vascular disorder: Other examples of autoinflammatory disorders with disease-causing mosaicism in genes known to cause germline disease include Blau syndrome (NOD2) [33], tumor necrosis factor receptor associated periodic syndrome (TRAPS, TNFRSF1A) [32], and STING-associated vasculopathy with onset in infancy (SAVI, TMEM173) [35, 36].