Jun et al. also reported that gram-negative Salmonella infection constitutively activated β-catenin and thereby stabilized IκBα, which subsequently repressed the activity of NF-κB in HCT116 colon cancer cells39, indicating that the crosstalk between the Wnt/β-catenin and NF-κB pathways is linked to the regulation of inflammation. The gene discussed is NFKB1; the disease is colonic neoplasm.