To test whether DUSP16 regulates the response of cancer cells to other chemotherapy drugs, we treated NPC cells HK-1 and C666-1 with carboplatin which is used for treating NPC62, and CRC cells DLD-1 and HCT116 with oxaliplatin which is used in the management of metastatic colorectal cancer63. This evidence concerns the gene DUSP16 and cancer.