Similar to analysis of the change in the GABRG2 level in the NAc, analysis of the change in the mRNA level of GABRG2 in the PFC revealed a significant effect of age [F(1, 32) = 12.244, P < 0.05] and CIS exposure (F(1, 32) = 4.201, P < 0.05) but not their interaction. This evidence concerns the gene GABRG2 and in situ carcinoma.