CRP and malaria: Recent more advanced clinical charts, also built on electronic tools, such as electronic point-of-care tests (ePOCT) integrating malaria RDT, haemoglobin, pulse oximetry in all febrile patients and other tests (e.g. glucometer, C-reactive protein) in subgroups of them, have led to major improvements in febrile disease classification and a considerable reduction of antibiotic prescription [27].