SHMT2 and neoplasm: Analysis of the relationships among a series of clinicopathological features revealed that expression of SHMT2 was significantly associated with age (P = 0.03), pathologic tumor stage (P = 0.016), pathologic lymph node metastasis (P = 0.039) and clinical stage (P = 0.004), alcohol history (P = 0.005) and margin status (P = 0.045).