BIRC5 and head and neck squamous cell carcinoma: Survivin was significantly associated with poorer OS in HNSCC patients, with HR values of 2.02, similar results were found in subgroup analysis stratified by cancer type, such as LSCC, OSCC, NPC, etc. Significant correlation between survivin and shorter DFS/ DSS (HR 2.03/ HR 1.92, respectively) was also observed.