As several studies indicated an association with the occurrence of infection or reported contradictory information about such an association with polymorphisms in TLR4, IFN-γ, IL10, IL37 or TNF-α, we analyzed, as part of the prospective VIPP study mentioned above, single nucleotide polymorphisms (SNPs) in CMV-positive renal allograft recipients. This evidence concerns the gene IL37 and infection.