SUFU and medulloblastoma: In a large series of medulloblastomas screened for germline mutations, all SUFU or PTCH1 PVs were observed exclusively in the SHH-medulloblastoma (SHH-MB) subgroup, with a frequency of 17/80 (21%) and 18/170 (11%) in infant and pediatric SHH MB, respectively [17].