TNBC is a pressing area of research for both researchers and clinicians alike because (1) TNBC is a poor prognostic factor for disease-free and overall survival, (2) no targeted therapy is readily available for TNBC, (3) there is a clustering of TNBC cases specifically in premenopausal women and in women of African descent, and (4) the overlap of BRCA1-associated breast cancers with the TNBC phenotype is significant [1,3,10,13–15]. Here, BRCA1 is linked to breast carcinoma.