The top ten enriched score values of the significantly enriched pathways for these upregulated tRFs and tiRNAs are mucin-type O-glycan biosynthesis, glycosphingolipid biosynthesis, glucagon signaling pathway, AMPK signaling pathway, maturity-onset diabetes of the young, glycosphingolipid biosynthesis, insulin signaling pathway, insulin resistance, leukocyte transendothelial migration, starch, and sucrose metabolism (Figure 8). This evidence concerns the gene GCG and type 2 diabetes mellitus.