The enriched score values of the significantly enriched pathways for DETs are mucin-type O-glycan biosynthesis, glycosphingolipid biosynthesis, glucagon signaling pathway, AMPK signaling pathway, maturity-onset diabetes of the young, glycosphingolipid biosynthesis, insulin signaling pathway, insulin resistance, leukocyte transendothelial migration, starch and sucrose metabolism, other glycan degradation, vitamin digestion and absorption, fatty acid elongation, and biosynthesis of unsaturated fatty acids. The gene discussed is INS; the disease is type 2 diabetes mellitus.