For example, lncRNA MALAT-1 has been found to be upregulated in various malignant tumors, and upregulated MALAT-1 is remarkably linked to worse OS (overall survival) or DFS (disease-free survival) in individuals with gastrointestinal carcinomas (Chen D. et al., 2017; Wu et al., 2018). Here, MALAT1 is linked to digestive system carcinoma.