Lymphopenia  Lymphocyte subsets - ↓CD4+, CD8+, B, NK cells,  ↑ plasma cells  ↑ NLR & ↓ LCR  ↑ IL-2R/Lymphocytes ratio  ↑ IL-6  ↑ CRP, PCT  ↑ Ferritin  ↑ LDH  ↑ D-dimers  ↑ Specific cardiac biomarkers – CK-MB, CTnT, Mb, NT-proBNP. The gene discussed is NPPB; the disease is lymphopenia.