DE-mRNAs were significantly enriched in metabolic and cancer-associated pathways including metabolic pathways, biosynthesis of amino acids, alanine, aspartate, and glutamate metabolism, the PI3K-Akt signaling pathway, the TGF-β signaling pathway, cell adhesion molecules (CAMs), the Jak-STAT signaling pathway, the MAPK signaling pathway, and the Rap1 signaling pathway. The gene discussed is TGFB1; the disease is cancer.