Fibroblast growth factor receptor 2 (FGFR2) and fibroblast growth factor 12 (FGF12) are the members of the fibroblast growth factor family, which is involved in the activation of the Kirsten Rat Sarcoma (RAS)-Mitogen-Activated Protein Kinase (MAPK) and the Threonine Kinase (AKT) and the PI3K–AKT pathway, and the cell proliferation, differentiation, and apoptosis of cancers (30). The gene discussed is AKT1; the disease is cancer.