While KEGG pathway analysis showed enrichment mainly in ECM-receptor interaction, PI3K-Akt signaling pathway, platelet activation, protein digestion and absorption, hematopoietic cell lineage, osteoclast differentiation, amoebiasis, focal adhesion, Rap1 signaling pathway, asthma, neuroactive ligand–receptor interaction, malaria, axon guidance, phagosome, Ras signaling pathway (Fig. 4B). This evidence concerns the gene AKT1 and asthma.