WEE1 and glioblastoma: All 49 protein kinases targeted by the 31 hypoxic-selective inhibitors were scored individually according to their interaction with HIF-1α and network topology in addition to the predicted GBM patients' survival based on their expression status retrieved from PRECOG 21, TCGA 22, and CGGA 23 to strengthen the robustness and clinical relevance of the analysis (Figure 1D).