There are very few mutated antigens described where the mutated peptide is shared across patients or cancer types, the most studied shared mutations are KRAS  (35), NRAS (36), epitopes from BCR-ABL translocation (Chronic myeloid leukemia) (37, 38), ETV6 (acute myeloid leukemia) (39), NPM/ALK (anaplastic large cell lymphomas) (40, 41) and ALK (neuroblastoma) (42, 43). The gene discussed is ALK; the disease is cancer.