Though there is a strong correlation between NfL levels in serum and CSF (Spearman Rho = 0.60, R2 = 0.34 and p < 0.0001; Figure 3B and Supplementary Table 1), sNfL is not statistically significantly different between active and inactive MS subgroups (unadjusted p = 0.0690; Table 4, and Figure 3A). The gene discussed is NEFL; the disease is myeloid sarcoma.