At admission, lymphocytes count was similar in COPD+ with SERPINA1 hypermethylation (1.97 × 103 ± 0.92 cell/μl) and COPD+ with SERPINA1 hypomethylation (1.88 × 103 ± 1.05 cell/μl) (p > 0.05; Fig. 4c), as well as in COPD− with SERPINA1 hypermethylation (2.16 × 103 ± 0.95 cell/μl) and COPD− with hypomethylation (2.11 × 103 ± 1.01 cell/μl) (p > 0.05; Fig. 4c). The gene discussed is SERPINA1; the disease is chronic obstructive pulmonary disease.