SERPINA1 and chronic obstructive pulmonary disease: At discharge, lymphocytes count was similar in COPD+ with SERPINA1 hypermethylation (1.81 × 103 ± 0.69 cell/μl) and COPD+ with hypomethylation (1.42 × 103 ± 0.73) (p > 0.05; Fig. 4d), whereas it was found to be higher in COPD− with SERPINA1 hypermethylation (1.98 × 103 ± 0.6 cell/μl) than in COPD− with SERPINA1 hypomethylation (1.7 × 103 ± 0.48 cell/μl) (p < 0.05, Fig. 4d).