The correlation between STING and cGAS levels showed that before therapy there was a greater positive correlation than after the use of ART, showing that the infection induces the continuous expression of the two restriction factors for activation of innate immunity mechanisms against HIV-1 infection, while the use of HAART influenced the reduction in the levels of factors, which resulted in a reduction in the correlation between both. The gene discussed is STING1; the disease is HIV-1 infection.