The results demonstrate that fatty acid metabolism, cell cycle, PPAR signalling pathway, pathways in cancer, p53 signalling pathway, Wnt signalling pathway, MAPK signalling pathway, TGF beta signalling pathway, melanoma, prostate cancer, acute myeloid leukaemia and others are correlated with H2AFY. The gene discussed is MACROH2A1; the disease is prostate carcinoma.