PTEN and hepatocellular carcinoma: LncRNA XIST promoted the expression of target gene PTEN of miR-181a by targeting and binding to miR-181a, thus accelerating the development process of HCC (Chang et al. 2017).The directly targeting relationship between LncRNA XIST and miR-192 was reported in previous study, but the relationship was still not clear in HCC cells (Gu et al. 2019).