Similarly, PAI-1 activity was enhanced in the T2DM participants with poor glycemic control [4.76 U/mL (4.19–6.02)] than both the participants with good glycemic control [4.49 U/mL (4.06–5.60)] and the control group [4.12 U/mL (3.44–4.45)] (Table 2). Here, SERPINE1 is linked to type 2 diabetes mellitus.