GPT and kidney disorder: Additionally, there was no difference in the serum levels of aspartate aminotransferase (1-way ANOVA, F4,15 = 1.09, P = 0.40), alanine aminotransferase (F4,15 = 1.28, P = 0.32), albumin (F4,15 = 0.36, P = 0.83), and creatinine (F4,15 = 1.72, P = 0.20) in rats treated with haloperidol, acetaminophen, or both for 21 days (Supplemental Figure 3, C–F); however, acetaminophen overdose is known to induce hepatopathy and nephropathy in humans (10, 11).