KLK3 and posterior cortical atrophy: For patients with a life expectancy of > 10-15 years with the diagnosis of intermediate-risk PCa, a PSA level of < 20 ng/mL, and disease confined to the prostate, the panel reached consensus in recommending radical prostatectomy for patients with Gleason score 3 + 4 or 4 + 3, even in institutions where there is no availability of IMRT technique, conformal external beam radiotherapy, and robotic surgery, including in areas of limited resources.