NR4A2 and early-onset autosomal dominant Alzheimer disease: It is imperative to correctly understand the functional brain organization patterns of this gene, as mutations of human NR4A2 have been linked to schizophrenia (Buervenich et al., 2000), Parkinson's Disease (Liu et al., 2017), and neuroprotection for Alzheimer's Disease (Moon et al., 2019).