After adjusting for age, there was a significant negative univariate correlation between serum sclerostin and carotid intima‐media thickness in the diabetes group (r = ‒0.42; P = .006) and between serum Dkk‐1 and carotid intima‐media thickness in the diabetes group (r = ‒0.48; P = .001); no significant correlations were seen between these serum markers and carotid intima‐media thickness in the control group.46 This evidence concerns the gene SOST and diabetes mellitus.