Mean (± standard error of the mean [SEM]) urine and plasma concentrations of MMP‐2 were significantly elevated in people with type 1 diabetes (n = 93) compared with age‐matched healthy volunteers (n = 50) (urine, pg/mL: diabetes group, 184.9 ± 31.3; control group, 48.4 ± 10.2; P < .001; plasma, mg/mL: diabetes group, 274.0 ± 20.0; control group, 191.2 ± 14.5; P < .005).52 This evidence concerns the gene MMP2 and type 1 diabetes mellitus.