SFRP4 and Abnormality of connective tissue: To determine whether the loci of Dupuytren disease‐associated variants were involved in susceptibility to Peyronie's disease, SNPs in 9 genes (WNT4, SFRP4, WNT2, SULF1, RSPO2, doublesex and mab‐3 related transcription factor 2 [DMRT2], zinc finger protein 264 [ZNF264], MAF bZIP transcription factor B [MAFB] and WNT7B) previously identified in a GWAS33 were genotyped in 111 men with Peyronie's disease and 490 male controls.36