TIMP1 and type 1 diabetes mellitus: A subsequent study in participants with type 1 diabetes (n = 47; age ± SD, 40 ± 14 years; range, 20‐65 years) reported that MMP‐9 was significantly increased in the systemic circulation compared with controls (n = 35; age ± SD, 41 ± 9 years; range, 24‐56 years; P < .001),53 while nonsignificant increases in serum TIMP‐1 were observed in participants with type 1 diabetes versus controls (P = .07).53