No significant differences were observed by mRNA expression or immunohistochemical staining for WNT4, RSPO2 or SULF1. 42Immunohistochemical staining of β‐catenin was significantly higher in Dupuytren disease nodules, specifically in the nucleus (P < .05), compared with normal tissues.42 The gene discussed is WNT4; the disease is Dupuytren Contracture.